Glutamate transporter control of ambient glutamate levels

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Glutamate transporter control of ambient glutamate levels

Accurate knowledge of the ambient extracellular glutamate concentration in brain is required for understanding its potential impacts on tonic and phasic receptor signaling. Estimates of ambient glutamate based on microdialysis measurements are generally in the range of ∼2-10μM, approximately 100-fold higher than estimates based on electrophysiological measurements of tonic NMDA receptor activit...

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ژورنال

عنوان ژورنال: Neurochemistry International

سال: 2014

ISSN: 0197-0186

DOI: 10.1016/j.neuint.2014.04.007